原著論文Original Articles

2024年

ワクチン創成グループ 

  1. Humoral and cellular immune responses to COVID-19 mRNA vaccines in immunosuppressed liver transplant recipients. Nogimori T, Nagatsuka Y, Kobayashi S, Murakami H, Masuta Y, Suzuki K, Tomimaru Y, Noda T, Akita H, Takahama S, Yoshioka Y, Doki Y, Eguchi H, Yamamoto T. Commun Med (Lond). 2024 Feb 26;4(1):30.

  2. An inactivated whole-virion vaccine for Enterovirus D68 adjuvanted with CpG ODN or AddaVax elicits potent protective immunity in mice. Senpuku K, Kataoka-Nakamura C, Kunishima Y, Hirai T, Yoshioka Y. Vaccine. 2024 Apr 2;42(9):2463-2474.

  3. Adjuvant-free parenterally injectable vaccine platform that harnesses previously induced IgG as an antigen delivery carrier Kawai A, Hirata H, Tokunoh N, Ono C, Matsuura Y, Hirai T,Yoshioka Y. Biochem Biophys Res Commun. 2024 Apr 7;711:149919.

  4. Adoptively Transferred Myeloid-Derived Suppressor Cells Decrease Influenza A Virus Infection Mortality in a Mouse Model. Xie Z, Kawai A, Watanabe N, Okada N, Yoshioka Y, Tachibana M. BPB Reports. 2024;7(2):26-32.

  5. JAK inhibition during the early phase of SARS-CoV-2 infection worsens kidney injury by suppressing endogenous antiviral activity in mice. Sakai H, Kamuro H, Tokunoh N, Izawa T, Tamiya S, Yamamoto A, Tanaka S, Okuzaki D, Ono C, Matsuura Y, Okada Y, Yoshioka Y, Fujio Y, Obana M. Am J Physiol Renal Physiol. 2024 Apr 18.

  6. Lipid Nanoparticle with 1,2-Di-O-octadecenyl-3-trimethylammonium-propane as a Component Lipid Confers Potent Responses of Th1 Cells and Antibody against Vaccine Antigen. Kawai A, Noda M, Hirata H, Munakata L, Matsuda T, Omata D, Takemura N, Onoe S, Hirose M, Kato T, Saitoh T, Hirai T, Suzuki R, Yoshioka Y. ACS Nano. 2024 Jun 17. doi: 10.1021/acsnano.4c00278. Online ahead of print.

ウイルスワクチングループ 

  1. Vero cell-adapted SARS-CoV-2 strain shows increased viral growth through furin-mediated efficient spike cleavage
    Minami S, Kotaki T, Sakai Y, Okamura S, Torii S, Ono C, Motooka D, Hamajima R, Nouda R, Nurdin JA, Yamasaki M, Kanai Y, Ebina H, Maeda Y, Okamoto T, Tachibana T, Matsuura Y, Kobayashi T.Microbiol Spectr. 2024 Apr 2;12(4):e0285923. doi: 10.1128/spectrum.02859-23. Epub 2024 Feb 28.PMID: 38415690 

  2. Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms
    Mie Suzuki-Okutani,Shinya Okamura,Tang Gis,Hitomi Sasaki,Suni Lee,Akiho Yoshida,Simon Goto,Tatsuya Nakagawa,Masahito Ikawa,Hirotaka Ebina.
    eLi
    fe, https://doi.org/10.7554/eLife.97532.1

  3. 1mΨ influences the performance of various positive-stranded RNA virus-based replicons
    Paola Miyazato, Takafumi Noguchi, Fumiyo Ogawa, Takeshi Sugimoto, Yuzy Fauzyah, Ryo Sasaki & Hirotaka Ebina 
    Scientific Reports volume 14, Article number: 17634 

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